Name | Pyridine Hydrochloride |
Synonyms | PYRIDINE HCL Pyridinium chloride PYRIDINIUM CHLORIDE Pyridine Hydrochloride PYRIDINE HYDROCHLORIDE PYRIDINIUM MONOCHLORIDE PYRIDINE HYDROCHLORIDE PYRIDINE HYDROCHLORIDE |
CAS | 628-13-7 |
EINECS | 211-027-4 |
InChI | InChI=1/C5H5N.ClH/c1-2-4-6-5-3-1;/h1-5H;1H |
InChIKey | AOJFQRQNPXYVLM-UHFFFAOYSA-N |
Molecular Formula | C5H6ClN |
Molar Mass | 115.56 |
Density | 1.1182 (rough estimate) |
Melting Point | 145-147°C(lit.) |
Boling Point | 222-224°C(lit.) |
Flash Point | 222-224°C |
Water Solubility | 85 g/100 mL |
Solubility | ethanol: soluble50mg/mL, clear, colorless to light yellow |
Vapor Presure | 22.8mmHg at 25°C |
Appearance | White Crystals |
Color | White to tan |
BRN | 3615340 |
Storage Condition | Inert atmosphere,Room Temperature |
Stability | Hygroscopic |
Sensitive | Hygroscopic |
Refractive Index | 1.5304 (estimate) |
MDL | MFCD00012802 |
Physical and Chemical Properties | Melting point 140-146°C. Boiling Point 222-224°C. Water-soluble 85g/100. |
Use | Pharmaceutical Intermediates |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | UT4375000 |
FLUKA BRAND F CODES | 3-10 |
TSCA | Yes |
HS Code | 29333100 |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
Introduction | pyridine, an organic compound, is a six-membered heterocyclic compound containing a nitrogen heteroatom. Can be seen as one of the benzene molecules (CH) substituted by N compounds, so also known as nitrogen benzene, colorless or yellowish liquid, there is a smell. Pyridine and its homologs are found in bone tar, coal tar, gas, shale oil, and petroleum. Pyridine in the industry can be used as denaturants, dyeing AIDS, and synthesis of a series of products (including drugs, disinfectants, dyes, etc.) of raw materials. Pyridine hydrochloride is the hydrochloride state of pyridine. |
Application | pyridine hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, can be used in laboratory research and development process and chemical pharmaceutical production process, it is also one of the raw materials for the production of methyl erythromycin. |
preparation method | dry hydrochloric acid gas can be introduced into pyridine for direct salt formation. Specific Method: reaction bottle containing 100g of sodium chloride, concentrated hydrochloric acid 200 ml under stirring, Dropwise and concentrated sulfuric acid to produce hydrochloric acid gas, after drying by concentrated sulfuric acid, into the ice water bath cooling pure pyridine solution, preparation of pyridine hydrochloride. |
uses | used as pharmaceutical intermediates pyridine hydrochloride is mainly used in pharmaceutical intermediates, biochemical research, organic synthesis; it is also one of the raw materials for the production of methyl erythromycin. |